Weight loss injections: The benefits are as great as the risks – affecting the kidneys, liver, and heart..
- byShikha Srivastava
- 29 Sep, 2025
In today's fast-paced life, the desire to lose weight has become increasingly common. People try everything from diet plans to gyms and medications. In recent years, GLP-1 injections like semaglutide and liraglutide have become a major trend. Many celebrities and ordinary people, from Hollywood to India, have adopted them. But the question remains: are these injections truly safe, or are they simply creating new risks within the body?

How do these injections work?
GLP-1 injections reduce appetite and maintain blood sugar balance. Initially used for diabetes control, their potential for weight loss has led to their adoption in obesity management. Demand for them has rapidly increased among those suffering from obesity.
What are the proven benefits?
- Clinical studies found that those taking semaglutide lost 15-20% of their weight.
- A report from the American Heart Association states that it also reduces the risk of heart attack and stroke.
- Positive effects were also seen on obesity-related problems like diabetes, blood pressure, and cholesterol.
But the risks are not without.
Every medication comes with a downside. These weight-loss injections have also been associated with some serious side effects.
Kidney effects – Patients with pre-existing kidney problems have reported conditions like kidney failure after receiving the injections.
Liver and pancreas – Nausea, vomiting, and diarrhea are common side effects, but pancreatitis and gallbladder-related diseases have also been reported in some cases.
Heart risks – While these medications are said to be beneficial for the heart, drug interactions and personal medical history can cause adverse effects in some people.
Experts warn
Experts say that while weight-loss injections have been effective in many patients, they are not a self-administered medication. People with kidney, liver, or pancreas problems should not take these without a doctor's supervision. Baseline tests such as kidney function tests, liver function tests, and blood sugar tests should be performed before starting the medication. If symptoms such as persistent vomiting, jaundice, decreased urine output, or severe abdominal pain occur during treatment, consult a doctor immediately.

What to take and what to avoid?
- Never start injections without consulting a specialist.
- Regularly undergo kidney and liver tests.
- If you experience side effects, stop the medication immediately and consult a doctor.
- Don't neglect diet and exercise, as these are the safest and most sustainable methods of weight loss.
Weight loss injections have certainly brought new hope to medical science and can prove helpful for those struggling with obesity. But they are not a magic shot. The benefits are as great as the side effects. Therefore, if you are considering using them, do so only under the guidance and supervision of a doctor. Otherwise, it can slowly damage your kidneys, liver and heart.
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